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Nitric Oxide-cGMP Signaling Stimulates Erythropoiesis through Multiple Lineage-Specific Transcription Factors: Clinical Implications and a Novel Target for Erythropoiesis

Much attention has been directed to the physiological effects of nitric oxide (NO)-cGMP signaling, but virtually nothing is known about its hematologic effects. We reported for the first time that cGMP signaling induces human γ-globin gene expression. Aiming at developing novel therapeutics for anem...

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Опубликовано в: :PLoS One
Главные авторы: Ikuta, Tohru, Sellak, Hassan, Odo, Nadine, Adekile, Adekunle D., Gaensler, Karin M. L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699757/
https://ncbi.nlm.nih.gov/pubmed/26727002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144561
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