Colonic Hypersensitivity and Sensitization of Voltage-gated Sodium Channels in Primary Sensory Neurons in Rats with Diabetes

BACKGROUND/AIMS: Patients with long-standing diabetes often demonstrate intestinal dysfunction and abdominal pain. However, the pathophysiology of abdominal pain in diabetic patients remains elusive. The purpose of study was to determine roles of voltage-gated sodium channels in dorsal root ganglion...

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Veröffentlicht in:J Neurogastroenterol Motil
Hauptverfasser: Hu, Ji, Song, Zhen-Yuan, Zhang, Hong-Hong, Qin, Xin, Hu, Shufen, Jiang, Xinghong, Xu, Guang-Yin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society of Neurogastroenterology and Motility 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699730/
https://ncbi.nlm.nih.gov/pubmed/26459453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5056/jnm15091
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