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Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent

Hepatocellular carcinoma (HCC) remains a global health threat. The search for novel anti-HCC agents is urgent. In the current study, we synthesized a liposomal C8 ceramide, and analyzed its anti-tumor activity in pre-clinical HCC models. The liposomal C8 (ceramide) potently inhibited HCC cell (HepG2...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lv, Huiqing, Zhang, Zhongmin, Wu, Xiaoyu, Wang, Yaoxia, Li, Chenglin, Gong, Weihong, Gui, Liang, Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699687/
https://ncbi.nlm.nih.gov/pubmed/26727592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145195
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