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Alliance A091103 a phase II study of the angiopoietin 1 and 2 peptibody trebananib for the treatment of angiosarcoma
INTRODUCTION: Angiosarcomas are rare malignant endothelial cell tumors which have up-regulation of the angiopoietin system [e.g., Tie2 and Angiopoietin 2 (Ang2)]. Trebananib is a novel agent targeting Angiopoietin 1 and Angiopoietin 2. METHODS: Trebananib 30 mg/kg was administered weekly until progr...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699670/ https://ncbi.nlm.nih.gov/pubmed/25672915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2689-8 |
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