Structures of minute virus of mice replication initiator protein N-terminal domain: insights into DNA nicking and origin binding

Members of the Parvoviridae family all encode a non-structural protein 1 (NS1) that directs replication of single-stranded viral DNA, packages viral DNA into capsid, and serves as a potent transcriptional activator. Here we report the X-ray structure of the minute virus of mice (MVM) NS1 N-terminal...

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Bibliographic Details
Published in:Virology
Main Authors: Tewary, Sunil Kumar, Liang, Lingfei, Lin, Zihan, Lynn, Annie, Cotmore, Susan F., Tattersall, Peter, Zhao, Haiyan, Tang, Liang
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699654/
https://ncbi.nlm.nih.gov/pubmed/25528417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.11.022
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