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Polymorphs of Theophylline Characterized by DNP Enhanced Solid-State NMR
[Image: see text] We show how dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy can be used to characterize polymorphs and solvates of organic solids. We applied DNP to three polymorphs and one hydrated form of the asthma drug molecule theophylline. For some forms of theophyll...
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| Veröffentlicht in: | Mol Pharm |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2015
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699642/ https://ncbi.nlm.nih.gov/pubmed/26393368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00610 |
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