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Polymorphs of Theophylline Characterized by DNP Enhanced Solid-State NMR

[Image: see text] We show how dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy can be used to characterize polymorphs and solvates of organic solids. We applied DNP to three polymorphs and one hydrated form of the asthma drug molecule theophylline. For some forms of theophyll...

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Bibliografske podrobnosti
izdano v:Mol Pharm
Main Authors: Pinon, Arthur C., Rossini, Aaron J., Widdifield, Cory M., Gajan, David, Emsley, Lyndon
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2015
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699642/
https://ncbi.nlm.nih.gov/pubmed/26393368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00610
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