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Lacrimal Gland Inflammation Deregulates Extracellular Matrix Remodeling and Alters Molecular Signature of Epithelial Stem/Progenitor Cells

PURPOSE: The adult lacrimal gland (LG) is highly regenerative and is able to repair itself even after substantial damage; however, this ability to regenerate is lost with the development of dry eye conditions in chronically inflamed LGs.This study compares changes in the cell adhesion and cell matri...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Umazume, Takeshi, Thomas, William M., Campbell, Sabrina, Aluri, Hema, Thotakura, Suharika, Zoukhri, Driss, Makarenkova, Helen P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699416/
https://ncbi.nlm.nih.gov/pubmed/26747770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17477
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