Role of Matrix Metalloproteinases 2 and 9 in Lacrimal Gland Disease in Animal Models of Sjögren's Syndrome

PURPOSE: Chronic inflammation of the lacrimal gland results in changes in the composition of the extracellular matrix (ECM), which is believed to compromise tissue repair. We hypothesized that increased production/activity of matrix metalloproteinases (MMPs), especially MMP-2 and -9, in inflamed lac...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Aluri, Hema S., Kublin, Claire L., Thotakura, Suharika, Armaos, Helene, Samizadeh, Mahta, Hawley, Dillon, Thomas, William M., Leavis, Paul, Makarenkova, Helen P., Zoukhri, Driss
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530776/
https://ncbi.nlm.nih.gov/pubmed/26244298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17003
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