Local compartment changes and regulatory landscape alterations in histone H1-depleted cells

BACKGROUND: Linker histone H1 is a core chromatin component that binds to nucleosome core particles and the linker DNA between nucleosomes. It has been implicated in chromatin compaction and gene regulation and is anticipated to play a role in higher-order genome structure. Here we have used a combi...

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Gepubliceerd in:Genome Biol
Hoofdauteurs: Geeven, Geert, Zhu, Yun, Kim, Byung Ju, Bartholdy, Boris A., Yang, Seung-Min, Macfarlan, Todd S., Gifford, Wesley D., Pfaff, Samuel L., Verstegen, Marjon J. A. M., Pinto, Hugo, Vermunt, Marit W., Creyghton, Menno P., Wijchers, Patrick J., Stamatoyannopoulos, John A., Skoultchi, Arthur I., de Laat, Wouter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699363/
https://ncbi.nlm.nih.gov/pubmed/26700097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0857-0
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