Local compartment changes and regulatory landscape alterations in histone H1-depleted cells

BACKGROUND: Linker histone H1 is a core chromatin component that binds to nucleosome core particles and the linker DNA between nucleosomes. It has been implicated in chromatin compaction and gene regulation and is anticipated to play a role in higher-order genome structure. Here we have used a combi...

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Bibliografski detalji
Izdano u:Genome Biol
Glavni autori: Geeven, Geert, Zhu, Yun, Kim, Byung Ju, Bartholdy, Boris A., Yang, Seung-Min, Macfarlan, Todd S., Gifford, Wesley D., Pfaff, Samuel L., Verstegen, Marjon J. A. M., Pinto, Hugo, Vermunt, Marit W., Creyghton, Menno P., Wijchers, Patrick J., Stamatoyannopoulos, John A., Skoultchi, Arthur I., de Laat, Wouter
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699363/
https://ncbi.nlm.nih.gov/pubmed/26700097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0857-0
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