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The Plant-Derived Chalcone 2,2′,5′-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia

Chalcones are plant metabolites with potential for therapeutic exploitation as antioxidant, anti-inflammatory, and antiproliferative agents. Here we explored the neuroprotective effects of 2,2′,5′-trihydroxychalcone (225THC), a potent antioxidant with radical-scavenging properties. 225THC was found...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Jiwrajka, Manasi, Phillips, Alexandra, Butler, Matt, Rossi, Miriam, Pocock, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699027/
https://ncbi.nlm.nih.gov/pubmed/26798424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6301712
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