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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex

WDR5 is a core component of SET1-family complexes that achieve transcriptional activation via methylation of histone H3 on Nζ of Lys4 (H3K4). The role of WDR5 in the MLL1 complex has recently been described as specific recognition of dimethyl-K4 in the context of a histone H3 amino terminus; WDR5 is...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Principais autores: Ruthenburg, Alexander J, Wang, Wooikoon, Graybosch, Daina M, Li, Haitao, Allis, C David, Patel, Dinshaw J, Verdine, Gregory L
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698793/
https://ncbi.nlm.nih.gov/pubmed/16829959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1119
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