Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors

BACKGROUND: The limited duration and compromised efficiency of oocyte-mediated reprogramming, which occurs during the early hours following somatic cell nuclear transfer (SCNT), may significantly interfere with epigenetic reprogramming, contributing to the high incidence of ill/fatal transcriptional...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Hosseini, Sayyed Morteza, Dufort, Isabelle, Nieminen, Julie, Moulavi, Fariba, Ghanaei, Hamid Reza, Hajian, Mahdi, Jafarpour, Farnoosh, Forouzanfar, Mohsen, Gourbai, Hamid, Shahverdi, Abdol Hossein, Nasr-Esfahani, Mohammad Hossein, Sirard, Marc-André
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698792/
https://ncbi.nlm.nih.gov/pubmed/26725231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2264-z
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