Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Genome-wide association studies of 146 plasma protein levels in 818 individuals revealed 56 genome-wide significant associations (28 novel) with 47 analytes. Loci associated with plasma levels of 39 proteins tested have been previously associated with various complex traits such as heart disease, in...

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Publicado no:Sci Rep
Main Authors: Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Del-Aguila, Jorge L., Fernandez, Maria Victoria, Carrell, David, Black, Kathleen, Budde, John, Ma, ShengMei, Saef, Benjamin, Howells, Bill, Bertelsen, Sarah, Bailey, Matthew, Ridge, Perry G., Holtzman, David, Morris, John C., Bales, Kelly, Pickering, Eve H., Lee, Jin-Moo, Heitsch, Laura, Kauwe, John, Goate, Alison, Piccio, Laura, Cruchaga, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698720/
https://ncbi.nlm.nih.gov/pubmed/36647296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18092
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