Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease

Activation of Kupffer cells (KCs) plays a central role in the pathogenesis of alcoholic liver disease (ALD). C57BL/6 mice fed EtOH-containing diet showed a mixed induction of hepatic classical (M1) and alternative (M2) macrophage markers. Since telomerase activation occurs at critical stages of myel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Wu, Xiao-qin, Yang, Yang, Li, Wan-xia, Cheng, Ya-hui, Li, Xiao-feng, Huang, Cheng, Meng, Xiao-ming, Wu, Bao-ming, Liu, Xin-hua, Zhang, Lei, Lv, Xiong-wen, Li, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698632/
https://ncbi.nlm.nih.gov/pubmed/26725521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18685
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