Increased systolic load causes adverse remodeling of fetal aortic and mitral valves

While abnormal hemodynamic forces alter fetal myocardial growth, little is known about whether such insults affect fetal cardiac valve development. We hypothesized that chronically elevated systolic load would detrimentally alter fetal valve growth. Chronically instrumented fetal sheep received eith...

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Veröffentlicht in:Am J Physiol Regul Integr Comp Physiol
Hauptverfasser: Tibayan, Frederick A., Louey, Samantha, Jonker, Sonnet, Espinoza, Herbert, Chattergoon, Natasha, You, Fanglei, Thornburg, Kent L., Giraud, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
Schlagworte:
Hormones, Reproduction and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698413/
https://ncbi.nlm.nih.gov/pubmed/26354842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00040.2015
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