The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions

The electrogenic sodium bicarbonate cotransporter (NBCe2) is encoded by SLC4A5, variants of which have been associated with salt sensitivity of blood pressure, which affects 25% of the adult population. NBCe2 is thought to mediate sodium bicarbonate cotransport primarily in the renal collecting duct...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Gildea, John J., Xu, Peng, Carlson, Julia M., Gaglione, Robert T., Bigler Wang, Dora, Kemp, Brandon A., Reyes, Camellia M., McGrath, Helen E., Carey, Robert M., Jose, Pedro A., Felder, Robin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Fluid and Electrolyte Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698408/
https://ncbi.nlm.nih.gov/pubmed/26447209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00150.2015
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