Tocilizumab for steroid refractory acute graft-versus-host disease

Acute graft-versus-host-disease (aGVHD) is a frequent and often lethal complication of allogeneic hematopoietic stem cell transplant despite prophylaxis. Tocilizumab is a humanized anti-IL-6 receptor monoclonal antibody that has evidence of activity in patients with steroid refractory (SR) GVHD. We...

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Gepubliceerd in:Leuk Lymphoma
Hoofdauteurs: Roddy, Julianna V. F., Haverkos, Bradley M., McBride, Ali, Leininger, Kathryn M., Jaglowski, Samantha, Penza, Sam, Klisovic, Rebecca, Blum, William, Vasu, Sumithira, Hofmeister, Craig C., Benson, Don M., Andritsos, Leslie A., Devine, Steven M., Efebera, Yvonne A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698359/
https://ncbi.nlm.nih.gov/pubmed/26140610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2015.1045896
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