Tocilizumab for steroid refractory acute graft-versus-host disease

Acute graft-versus-host-disease (aGVHD) is a frequent and often lethal complication of allogeneic hematopoietic stem cell transplant despite prophylaxis. Tocilizumab is a humanized anti-IL-6 receptor monoclonal antibody that has evidence of activity in patients with steroid refractory (SR) GVHD. We...

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Veröffentlicht in:Leuk Lymphoma
Hauptverfasser: Roddy, Julianna V. F., Haverkos, Bradley M., McBride, Ali, Leininger, Kathryn M., Jaglowski, Samantha, Penza, Sam, Klisovic, Rebecca, Blum, William, Vasu, Sumithira, Hofmeister, Craig C., Benson, Don M., Andritsos, Leslie A., Devine, Steven M., Efebera, Yvonne A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698359/
https://ncbi.nlm.nih.gov/pubmed/26140610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2015.1045896
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