Ortho-stabilized (18)F-azido click agents and application in PET imaging of single-stranded DNA aptamer

Azido (18)F-arenes are important and versatile building blocks for radiolabeling of biomolecules via Huisgen cycloaddition (‘click chemistry’) in positron emission tomography (PET). However, routine access of such clickable agents is challenged by inefficient multi-step and esoteric radiochemical ap...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Wang, Lu, Jacobson, Orit, Avdic, Din, Rotstein, Benjamin H., Weiss, Ido D., Collier, Lee, Chen, Xiaoyuan, Vasdev, Neil, Liang, Steven H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698351/
https://ncbi.nlm.nih.gov/pubmed/26308650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201505927
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