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Ortho-stabilized (18)F-azido click agents and application in PET imaging of single-stranded DNA aptamer

Azido (18)F-arenes are important and versatile building blocks for radiolabeling of biomolecules via Huisgen cycloaddition (‘click chemistry’) in positron emission tomography (PET). However, routine access of such clickable agents is challenged by inefficient multi-step and esoteric radiochemical ap...

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Bibliografische gegevens
Gepubliceerd in:Angew Chem Int Ed Engl
Hoofdauteurs: Wang, Lu, Jacobson, Orit, Avdic, Din, Rotstein, Benjamin H., Weiss, Ido D., Collier, Lee, Chen, Xiaoyuan, Vasdev, Neil, Liang, Steven H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698351/
https://ncbi.nlm.nih.gov/pubmed/26308650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201505927
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