Ortho-stabilized (18)F-azido click agents and application in PET imaging of single-stranded DNA aptamer

Azido (18)F-arenes are important and versatile building blocks for radiolabeling of biomolecules via Huisgen cycloaddition (‘click chemistry’) in positron emission tomography (PET). However, routine access of such clickable agents is challenged by inefficient multi-step and esoteric radiochemical ap...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Wang, Lu, Jacobson, Orit, Avdic, Din, Rotstein, Benjamin H., Weiss, Ido D., Collier, Lee, Chen, Xiaoyuan, Vasdev, Neil, Liang, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698351/
https://ncbi.nlm.nih.gov/pubmed/26308650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201505927
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