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Targeting cullin-RING ligases for cancer treatment: rationales, advances and therapeutic implications
New therapeutic intervention strategies for the treatment of human malignancies are always desired. Approval of bortezomib as a front-line treatment for multiple myeloma highlighted the significance of ubiquitin–proteasome system (UPS) as a promising therapeutic target. However, due to the broad imp...
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| Publicado no: | Cytotechnology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698256/ https://ncbi.nlm.nih.gov/pubmed/25899169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-015-9870-0 |
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