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Engineered heart tissues and induced pluripotent stem cells: macro- and microstructures for disease modeling, drug screening, and translational studies

Engineered heart tissue has emerged as a personalized platform for drug screening. With the advent of induced pluripotent stem cell (iPSC) technology, patient-specific stem cells can be developed and expanded into an indefinite source of cells. Subsequent developments in cardiovascular biology have...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Tzatzalos, Evangeline, Abilez, Oscar J., Shukla, Praveen, Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698222/
https://ncbi.nlm.nih.gov/pubmed/26428619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.09.010
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