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Transcriptomics Profiling of Alzheimer’s Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs

The underlying genetic variations of late-onset Alzheimer’s disease (LOAD) cases remain largely unknown. A combination of genetic variations with variable penetrance and lifetime epigenetic factors may converge on transcriptomic alterations that drive LOAD pathological process. Transcriptome profili...

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Podrobná bibliografie
Vydáno v:J Alzheimers Dis
Hlavní autoři: Magistri, Marco, Velmeshev, Dmitry, Makhmutova, Madina, Faghihi, Mohammad Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698155/
https://ncbi.nlm.nih.gov/pubmed/26402107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150398
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