The Estrogen Metabolite 16αOHE Exacerbates BMPR2-Associated PAH Through miR-29-Mediated Modulation of Cellular Metabolism

BACKGROUND: Pulmonary arterial hypertension (PAH) is a proliferative disease of the pulmonary vasculature which preferentially affects females. Estrogens, such as the metabolite 16α-hydroxyestrone (16αOHE), may contribute to PAH pathogenesis; and, alterations in cellular energy metabolism associate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circulation
Egile Nagusiak: Chen, Xinping, Talati, Megha, Fessel, Joshua P., Hemnes, Anna R., Gladson, Santhi, French, Jaketa, Shay, Sheila, Trammel, Aaron, Phillips, John A., Hamid, Rizwan, Cogan, Joy D., Dawson, Elliott P., Womble, Kristie E., Hedges, Lora K., Martinez, Elizabeth G., Wheeler, Lisa A., Loyd, James E., Majka, Susan J., West, James, Austin, Eric D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698046/
https://ncbi.nlm.nih.gov/pubmed/26487756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.016133
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