The Estrogen Metabolite 16αOHE Exacerbates BMPR2-Associated PAH Through miR-29-Mediated Modulation of Cellular Metabolism

BACKGROUND: Pulmonary arterial hypertension (PAH) is a proliferative disease of the pulmonary vasculature which preferentially affects females. Estrogens, such as the metabolite 16α-hydroxyestrone (16αOHE), may contribute to PAH pathogenesis; and, alterations in cellular energy metabolism associate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Circulation
मुख्य लेखकों: Chen, Xinping, Talati, Megha, Fessel, Joshua P., Hemnes, Anna R., Gladson, Santhi, French, Jaketa, Shay, Sheila, Trammel, Aaron, Phillips, John A., Hamid, Rizwan, Cogan, Joy D., Dawson, Elliott P., Womble, Kristie E., Hedges, Lora K., Martinez, Elizabeth G., Wheeler, Lisa A., Loyd, James E., Majka, Susan J., West, James, Austin, Eric D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698046/
https://ncbi.nlm.nih.gov/pubmed/26487756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.016133
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