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Role of Liver X Receptor in AD Pathophysiology

Alzheimer's disease (AD) is the major cause of dementia worldwide. The pharmacological activation of nuclear receptors (Liver X receptors: LXRs or Retinoid X receptors: RXR) has been shown to induce overexpression of the ATP-Binding Cassette A1 (ABCA1) and Apolipoprotein E (ApoE), changes that...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Sandoval-Hernández, Adrián G., Buitrago, Luna, Moreno, Herman, Cardona-Gómez, Gloria Patricia, Arboleda, Gonzalo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697813/
https://ncbi.nlm.nih.gov/pubmed/26720273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145467
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