Novel Zn(2+) Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents

Type 2 diabetes (T2D) occurs when there is insufficient insulin release to control blood glucose, due to insulin resistance and impaired β-cell function. The GPR39 receptor is expressed in metabolic tissues including pancreatic β-cells and has been proposed as a T2D target. Specifically, GPR39 agoni...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fjellström, Ola, Larsson, Niklas, Yasuda, Shin-ichiro, Tsuchida, Takuma, Oguma, Takahiro, Marley, Anna, Wennberg-Huldt, Charlotte, Hovdal, Daniel, Fukuda, Hajime, Yoneyama, Yukimi, Sasaki, Kazuyo, Johansson, Anders, Lundqvist, Sara, Brengdahl, Johan, Isaacs, Richard J., Brown, Daniel, Geschwindner, Stefan, Benthem, Lambertus, Priest, Claire, Turnbull, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697807/
https://ncbi.nlm.nih.gov/pubmed/26720709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145849
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados