Sildenafil inhibits the growth of human colorectal cancer in vitro and in vivo

Colorectal cancer is the third most common human cancer with frequent overexpression of the cGMP-specific phosphodiesterase 5 (PDE5). In the present study, we investigated that the anticancer effect of sildenafil on human colorectal cancer in vitro and in vivo, which is a potent and selective inhibi...

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Pubblicato in:Am J Cancer Res
Autori principali: Mei, Xiao-Long, Yang, Yang, Zhang, Yao-Jun, Li, Yong, Zhao, Jin-Ming, Qiu, Jian-Ge, Zhang, Wen-Ji, Jiang, Qi-Wei, Xue, You-Qiu, Zheng, Di-Wei, Chen, Yao, Qin, Wu-Ming, Wei, Meng-Ning, Shi, Zhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697679/
https://ncbi.nlm.nih.gov/pubmed/26807313
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