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BRD4 is a novel therapeutic target for liver fibrosis

Liver fibrosis is characterized by the persistent deposition of extracellular matrix components by hepatic stellate cell (HSC)-derived myofibroblasts. It is the histological manifestation of progressive, but reversible wound-healing processes. An unabated fibrotic response results in chronic liver d...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ding, Ning, Hah, Nasun, Yu, Ruth T., Sherman, Mara H., Benner, Chris, Leblanc, Mathias, He, Mingxiao, Liddle, Christopher, Downes, Michael, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697417/
https://ncbi.nlm.nih.gov/pubmed/26644586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522163112
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