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Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs

Enhancers are critical genomic elements that define cellular and functional identity through the spatial and temporal regulation of gene expression. Recent studies suggest that key genes regulating cell type-specific functions reside in enhancer-dense genomic regions (i.e., super enhancers, stretch...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hah, Nasun, Benner, Chris, Chong, Ling-Wa, Yu, Ruth T., Downes, Michael, Evans, Ronald M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311831/
https://ncbi.nlm.nih.gov/pubmed/25564661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424028112
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