Regulators of genetic risk of breast cancer identified by integrative network analysis

Genetic risk for breast cancer is conferred by a combination of multiple variants of small effect. To better understand how risk loci might combine, we examined whether risk-associated genes share regulatory mechanisms. We created a breast cancer gene regulatory network between transcription factors...

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Détails bibliographiques
Publié dans:Nat Genet
Auteurs principaux: Castro, Mauro AA, de Santiago, Ines, Campbell, Thomas M, Vaughn, Courtney, Hickey, Theresa E, Ross, Edith, Tilley, Wayne D, Markowetz, Florian, Ponder, Bruce AJ, Meyer, Kerstin B
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697365/
https://ncbi.nlm.nih.gov/pubmed/26618344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3458
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