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Brief optogenetic inhibition of dopamine neurons mimics endogenous negative reward prediction errors

Correlative studies have strongly linked phasic changes in dopamine activity with reward prediction error signaling. But causal evidence that these brief changes in firing actually serve as error signals to drive associative learning is more tenuous. While there is direct evidence that brief increas...

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Publicado en:Nat Neurosci
Autores principales: Chang, Chun Yun, Esber, Guillem R, Marrero-Garcia, Yasmin, Yau, Hau-Jie, Bonci, Antonello, Schoenbaum, Geoffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696902/
https://ncbi.nlm.nih.gov/pubmed/26642092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4191
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