Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis

BACKGROUND: We investigated sera from elderly subjects with and without age-related macular degeneration (AMD) for presence of autoantibodies (AAbs) against human macular antigens and characterized their identity. METHODS: Sera were collected from participants in the Age-Related Maculopathy Ancillar...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Iannaccone, Alessandro, Giorgianni, Francesco, New, David D., Hollingsworth, T. J., Umfress, Allison, Alhatem, Albert H., Neeli, Indira, Lenchik, Nataliya I., Jennings, Barbara J., Calzada, Jorge I., Satterfield, Suzanne, Mathews, Dennis, Diaz, Rocio I., Harris, Tamara, Johnson, Karen C., Charles, Steve, Kritchevsky, Stephen B., Gerling, Ivan C., Beranova-Giorgianni, Sarka, Radic, Marko Z.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696815/
https://ncbi.nlm.nih.gov/pubmed/26717306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145323
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