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Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2

SMYD proteins are an exciting field of study as they are linked to many types of cancer-related pathways. Cardiac and skeletal muscle development and function also depend on SMYD proteins opening a possible avenue for cardiac-related treatment. Previous crystal structure studies have revealed that t...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Spellmon, Nicholas, Sun, Xiaonan, Sirinupong, Nualpun, Edwards, Brian, Li, Chunying, Yang, Zhe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696779/
https://ncbi.nlm.nih.gov/pubmed/26717235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145758
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