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(R)-α-Lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for zGSH synthesis

Age-related depletion of GSH levels and perturbations in its redox state may be especially deleterious to metabolically active tissues, such as the heart and brain. We examined the extent and the mechanisms underlying the potential age-related changes in cerebral and myocardial GSH status in young a...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Suh, Jung H., Wang, Hong, Liu, Rui-Ming, Liu, JianKang, Hagen, Tory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696556/
https://ncbi.nlm.nih.gov/pubmed/14871476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2003.12.020
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