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Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome

Considerable progress towards an understanding of complex diseases has been made in recent years due to the development of high-throughput genotyping technologies. Using microarrays that contain millions of single-nucleotide polymorphisms (SNPs), Genome Wide Association Studies (GWASs) have identifi...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Tak, Yu Gyoung, Farnham, Peggy J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696349/
https://ncbi.nlm.nih.gov/pubmed/26719772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0050-4
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