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Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line

BACKGROUND: Next-generation sequencing (NGS) technologies have changed our understanding of the variability of the human genome. However, the identification of genome structural variations based on NGS approaches with read lengths of 35–300 bases remains a challenge. Single-molecule optical mapping...

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Publicado en:Gigascience
Main Authors: Teo, Audrey S. M., Verzotto, Davide, Yao, Fei, Nagarajan, Niranjan, Hillmer, Axel M.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696294/
https://ncbi.nlm.nih.gov/pubmed/26719794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13742-015-0106-1
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