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Antagonist of the neurokinin-1 receptor curbs neuroinflammation in ex vivo and in vitro models of Lyme neuroborreliosis

BACKGROUND: Lyme neuroborreliosis (LNB) can affect both the peripheral (PNS) and the central nervous systems (CNS); it is caused by the spirochete Borrelia burgdorferi. The neuropeptide substance P (SP) is an important mediator of both neuroinflammation and blood-brain barrier dysfunction, through i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neuroinflammation
मुख्य लेखकों: Martinez, Alejandra N., Ramesh, Geeta, Jacobs, Mary B., Philipp, Mario T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696197/
https://ncbi.nlm.nih.gov/pubmed/26714480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0453-y
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