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Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism

BACKGROUND: The metabolism of amyloid precursor protein (APP) and β-amyloid (Aβ) is widely studied in Alzheimer's disease, where Aβ deposition and plaque development are essential components of the pathogenesis. However, the physiological role of amyloid in the adult nervous system remains larg...

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Detalhes bibliográficos
Main Authors: Mattsson, Niklas, Bremell, Daniel, Anckarsäter, Rolf, Blennow, Kaj, Anckarsäter, Henrik, Zetterberg, Henrik, Hagberg, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902447/
https://ncbi.nlm.nih.gov/pubmed/20569437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-10-51
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