Corpus Callosum Diffusion Tensor Imaging and Volume Measures Are Associated With Disease Severity in Pediatric Niemann-Pick Disease Type C1

BACKGROUND: Niemann-Pick disease type C1 is a neurodegenerative lysosomal storage disorder. Without a highly effective treatment, biomarkers of severity would be beneficial for prognostication and testing new interventions. Diffusion tensor imaging has shown microstructural abnormalities in adults w...

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Detalhes bibliográficos
Publicado no:Pediatr Neurol
Main Authors: Lee, Ryan, Apkarian, Kalyna, Jung, Eun Sol, Yanjanin, Nicole, Yoshida, Shoko, Mori, Susumu, Park, Jina, Gropman, Andrea, Baker, Eva H., Porter, Forbes D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696056/
https://ncbi.nlm.nih.gov/pubmed/25194719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pediatrneurol.2014.07.028
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