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Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner

Insulin resistance is a condition in which cells are defective in response to the actions of insulin in tissue glucose uptake. Overstimulation of β-adrenergic receptors (βARs) leads to the development of heart failure and is associated with the pathogenesis of insulin resistance in the heart. Howeve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Mangmool, Supachoke, Denkaew, Tananat, Phosri, Sarawuth, Pinthong, Darawan, Parichatikanond, Warisara, Shimauchi, Tsukasa, Nishida, Motohiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695632/
https://ncbi.nlm.nih.gov/pubmed/26652903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1201
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