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Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner

Insulin resistance is a condition in which cells are defective in response to the actions of insulin in tissue glucose uptake. Overstimulation of β-adrenergic receptors (βARs) leads to the development of heart failure and is associated with the pathogenesis of insulin resistance in the heart. Howeve...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Mangmool, Supachoke, Denkaew, Tananat, Phosri, Sarawuth, Pinthong, Darawan, Parichatikanond, Warisara, Shimauchi, Tsukasa, Nishida, Motohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695632/
https://ncbi.nlm.nih.gov/pubmed/26652903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1201
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