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Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers

AIM: To study the influence of inducers of drug metabolism enzyme, β-naphthoflavone (BNF) and dexamethasone (DEX), on the stereoselective metabolism of propafenone in the rat hepatic microsomes. METHODS: Phase I metabolism of propafenone was studied using the microsomes induced by BNF and DEX and th...

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Détails bibliographiques
Publié dans:World J Gastroenterol
Auteurs principaux: Zhou, Quan, Yao, Tong-Wei, Zeng, Su
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695604/
https://ncbi.nlm.nih.gov/pubmed/11854911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v7.i6.830
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