eIF3 controls cell size independently of S6K1-activity

All multicellular organisms require a life-long regulation of the number and the size of cells, which build up their organs. mTOR acts as a signaling nodule for the regulation of protein synthesis and growth. To activate the translational cascade, mTOR phosphorylates S6 kinase (S6K1), which is liber...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Schipany, Katharina, Rosner, Margit, Ionce, Loredana, Hengstschläger, Markus, Kovacic, Boris
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695191/
https://ncbi.nlm.nih.gov/pubmed/26172298
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