MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway

Up to now, the molecular mechanisms underlying the stemness of prostate cancer stem cells (PCSCs) are still poorly understood. In this study, we demonstrated that microRNA-7 (miR-7) appears to be a novel tumor-suppressor miRNA, which abrogates the stemness of PCSCs and inhibits prostate tumorigenesi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Chang, Yun-Li, Zhou, Pei-Jie, Wei, Lianzi, Li, Wang, Ji, Zhongzhong, Fang, Yu-Xiang, Gao, Wei-Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695167/
https://ncbi.nlm.nih.gov/pubmed/26172296
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker