Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma

Dysregulated NF-κB signaling is critical for lymphomagenesis. The regulation, function, and clinical relevance of c-Rel/NF-κB activation in diffuse large B-cell lymphoma (DLBCL) have not been well studied. In this study we analyzed the prognostic significance and gene-expression signature of c-Rel n...

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Publicado en:Oncotarget
Autores principales: Li, Ling, Xu-Monette, Zijun Y., Ok, Chi Young, Tzankov, Alexandar, Manyam, Ganiraju C., Sun, Ruifan, Visco, Carlo, Zhang, Mingzhi, Montes-Moreno, Santiago, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W.L., van Krieken, J. Han, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael B., Wang, Jinfeng, Parsons, Ben M., Winter, Jane N., Piris, Miguel A., Pham, Lan V., Medeiros, L. Jeffrey, Young, Ken H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
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Priority Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695110/
https://ncbi.nlm.nih.gov/pubmed/26324762
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