Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma

Abnormal expression of the chemokine receptor CXCR4 plays an essential role in tumor cell dissemination and disease progression. However, the significance of CXCR4 overexpression in de novo diffuse large B cell lymphoma (DLBCL) is unknown. In 743 patients with de novo diffuse large B cell lymphoma (...

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Udgivet i:Oncotarget
Main Authors: Chen, Jiayu, Xu-Monette, Zijun Y., Deng, Lijuan, Shen, Qi, Manyam, Ganiraju C., Martinez-Lopez, Azahara, Zhang, Li, Montes-Moreno, Santiago, Visco, Carlo, Tzankov, Alexandar, Yin, Lihui, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W.L., van Krieken, J. Han, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Zhao, Xiaoying, Møller, Michael B., Farnen, John P., Winter, Jane N., Piris, Miguel A., Pham, Lan, Young, Ken H.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467389/
https://ncbi.nlm.nih.gov/pubmed/25704881
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