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Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma

Dysregulated NF-κB signaling is critical for lymphomagenesis. The regulation, function, and clinical relevance of c-Rel/NF-κB activation in diffuse large B-cell lymphoma (DLBCL) have not been well studied. In this study we analyzed the prognostic significance and gene-expression signature of c-Rel n...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Ling, Xu-Monette, Zijun Y., Ok, Chi Young, Tzankov, Alexandar, Manyam, Ganiraju C., Sun, Ruifan, Visco, Carlo, Zhang, Mingzhi, Montes-Moreno, Santiago, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W.L., van Krieken, J. Han, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael B., Wang, Jinfeng, Parsons, Ben M., Winter, Jane N., Piris, Miguel A., Pham, Lan V., Medeiros, L. Jeffrey, Young, Ken H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695110/
https://ncbi.nlm.nih.gov/pubmed/26324762
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