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p53-regulated autophagy is controlled by glycolysis and determines cell fate

The tumor suppressor p53 regulates downstream targets that determine cell fate. Canonical p53 functions include inducing apoptosis, growth arrest, and senescence. Non-canonical p53 functions include its ability to promote or inhibit autophagy and its ability to regulate metabolism. The extent to whi...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Duan, Lei, Perez, Ricardo E., Davaadelger, Batzaya, Dedkova, Elena N., Blatter, Lothar A., Maki, Carl G.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695109/
https://ncbi.nlm.nih.gov/pubmed/26337205
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