STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation

Brain metastases (BM) represent the most common tumor to affect the adult central nervous system. Despite the increasing incidence of BM, likely due to consistently improving treatment of primary cancers, BM remain severely understudied. In this study, we utilized patient-derived stem cell lines fro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Singh, Mohini, Garg, Neha, Venugopal, Chitra, Hallett, Robin, Tokar, Tomas, McFarlane, Nicole, Mahendram, Sujeivan, Bakhshinyan, David, Manoranjan, Branavan, Vora, Parvez, Qazi, Maleeha, Arpin, Carolynn C., Page, Brent, Haftchenary, Sina, Rosa, David A., Lai, Ping-Shan, Gómez-Biagi, Rodolfo F., Ali, Ahmed M., Lewis, Andrew, Geletu, Mulu, Murty, Naresh K., Hassell, John A., Jurisica, Igor, Gunning, Patrick T., Singh, Sheila K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695002/
https://ncbi.nlm.nih.gov/pubmed/26314961
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