Carfilzomib enhances natural killer cell-mediated lysis of myeloma linked with decreasing expression of HLA class I

Natural killer (NK) cell-based treatments are promising therapies for multiple myeloma (MM). Carfilzomib (CFZ), is a second-generation proteasome inhibitor, used to treat relapsed and refractory MM. In this study, we determined that CFZ treatment enhanced the sensitivity of MM cells to NK cell-media...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Guang, Gao, Minjie, Zhang, Yiwen, Kong, Yuanyuan, Gao, Lu, Tao, Yi, Han, Ying, Wu, Huiqun, Meng, Xiuqin, Xu, Hongwei, Zhan, Fenghuang, Wu, Xiaosong, Shi, Jumei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694968/
https://ncbi.nlm.nih.gov/pubmed/26323098
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